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Interhemispheric EEG Coherence as a Candidate Biomarker in Gambling Disorder: Evidence of Frontal Hyperconnectivity and Posterior Disconnectivity    
Yazarlar (3)
Dr. Öğr. Üyesi Eda YILMAZER Dr. Öğr. Üyesi Eda YILMAZER
Beykoz Üniversitesi, Türkiye
Sultan Tarlacı
Üsküdar Üniversitesi, Türkiye
Selami Varol Ülker
Üsküdar Üniversitesi, Türkiye
Devamını Göster
Özet
Background Gambling Disorder (GD) is a behavioral addiction marked by impaired decision-making and poor impulse control. We investigated whether resting-state interhemispheric quantitative EEG (qEEG) coherence—a measure of functional connectivity between homologous cortical regions—could serve as a biomarker of GD. Methods Twenty-nine male patients with GD and 45 healthy male controls underwent resting-state qEEG recording. Coherence was computed for homologous electrode pairs across delta, theta, alpha, and beta bands. Group differences were analyzed using independent-samples t-tests; associations with disorder duration were assessed via age-controlled partial correlations. Results Consistent with our hypothesis, GD participants exhibited frontal pole hypercoherence (Fp1– Fp2) across delta, theta, and beta bands, which is likely influenced by prefrontal/orbitofrontal generators. In …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Neuroscience Brain Imaging Methods
Dergi ISSN 1687112
Dergi Tarandığı Indeksler SSCI
Makale Dili İngilizce
Basım Tarihi 01-2025
Doi Numarası 10.3389/fnins.2025.1687112
Makale Linki https://myfrontiers.frontiersin.org/projects/submission/1687112