Delirium-associated disulfiram and ethanol interactions
Yazarlar (8)
Hasan Mirsal T.C. Maltepe Universitesi, Türkiye
Irem Yalug
Kocaeli Üniversitesi, Türkiye
Devran Tan T.C. Maltepe Universitesi, Türkiye
Theodore A. Stern Massachusetts General Hospital, Amerika Birleşik Devletleri
Ayhan Kalyoncu T.C. Maltepe Universitesi, Türkiye
Ozkan Pektas T.C. Maltepe Universitesi, Türkiye
Gamze Erdogan T.C. Maltepe Universitesi, Türkiye
Prof. Dr. Mansur BEYAZYÜREK T.C. Maltepe Universitesi, Türkiye
Makale Türü Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı Primary Care Companion to the Journal of Clinical Psychiatry
Dergi ISSN 1523-5998
Makale Dili İngilizce Basım Tarihi 01-2005
Kabul Tarihi Yayınlanma Tarihi 14-10-2005
Cilt / Sayı / Sayfa 7 / 5 / 235–237 DOI 10.4088/PCC.v07n0505
Makale Linki https://www.ncbi.nlm.nih.gov/pmc/articles/1257409
UAK Araştırma Alanları
Sağlık Bilimleri
Özet
Background: Disulfiram, an agent used for the treatment of alcohol dependence, can exacerbate psychiatric syndromes (including psychosis, catatonia, delirium, depression, and mania) after extended use. However, delirium has yet to be reported following the short-term use of disulfiram in the setting of alcohol use. Objectives: We report a case with a neuropsychiatric presentation and discuss the prevention and the progression of delirium associated with an interaction of disulfiram and ethanol. Case Report: We report the case of a 51-year-old woman who developed disorganized speech, diminished communication, a decrease in appetite, and thoughts of suicide 10 days after she began taking disulfiram (250 mg/day), to which she added 1 glass of alcoholic beverage for 2 days. Delirium developed in association with an interaction between disulfiram and alcohol. The patient met DSM-IV criteria for major depressive disorder, alcohol dependence, and delirium. Discussion: Neuropsychiatric manifestations may develop in association with co-administration of disulfiram and alcohol; timely recognition and treatment are recommended. © Copyright 2005 Physicians Postgraduate Press, Inc.
Anahtar Kelimeler
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Scopus 9
Delirium-associated disulfiram and ethanol interactions

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