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Postmortem Inductively Coupled Plasma Mass Spectrometry Analysis Reveals Elevated Heavy Metal Concentrations in Coronary Arteries: A Comparative Autopsy Study Supporting a Toxic Inflammatory Hypothesis for Atherosclerosis    
Yazarlar (12)
Onur Yolay
Türkiye
Prof. Dr. Emine Esra KASAPBAŞI Prof. Dr. Emine Esra KASAPBAŞI
Haliç Üniversitesi
Erdem Tezcan
Türkiye
Ceyhun Küçük
Türkiye
Hasan Karaoğlu
Emir Cankurt
Bekir İnan
Türkiye
Doğaç Okşen
Türkiye
Özge Çetinarslan
Türkiye
Fadıl Umuhanic
Serdar Baki Albayrak
Türkiye
Ayhan Olcay
Türkiye
Devamını Göster
Özet
Introduction A large number of studies have been carried out for the etiology of atherosclerosis and many risk factors have been identified, including environmental factors and heavy metals, which are related to the pathogenesis. Thjs study aimed to determine the effects of heavy metals, which have activation and inhibition effects on various metabolic pathways, on atherosclerosis by examining coronary arteries obtained from autopsy series. Methods Coronary arteries of twenty-eight autopsy cases were analyzed by inductively coupled plasma mass spectrometry method. sixteen of the cases had coronary atherosclerotic plaques and 12 of the coronaries were normal. Twenty trace metal concentrations were examined from the samples obtained. Results Twenty-eight coronary artery samples (16 with atherosclerosis, 12 normal) were analyzed using ICP-MS. Levels of Mg, K, Ca, P, Fe, Zn, Al, S, As, Pt, Sb, Hg were …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale
Dergi Adı Biomedicine Hub
Dergi ISSN 2296-6870
Dergi Tarandığı Indeksler Pubmed
Makale Dili Türkçe
Basım Tarihi 05-2025
Cilt No 10
Doi Numarası 10.1159/000546499
Makale Linki https://doi.org/10.1159/000546499