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OCULOMOTOR ABNORMALITIES IN PATIENTS WITH PARKINSON'S DISEASE AND PROGRESSIVE SUPRANUCLEAR PALSY    
Yazarlar (6)
K. Kocoglu
H. Eraslan Boz
Dr. Öğr. Üyesi Müge AKKOYUN Dr. Öğr. Üyesi Müge AKKOYUN
B. Donmez Colakoglu
R. Cakmur
G. Akdal
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Özet
Background: Deficits in the ocular fixation and gaze control to be key for Parkinsonism diagnosis. We aimed to find out the possible oculomotor differences between patients with idiopathic Parkinson's disease (PD) and progressive supranuclear palsy (PSP).Methods: Twenty-four patients with PD (age: 60.4±12.0; disease duration: 4.0±4.4 years), 12 with PSP (age: 67.2±11.1; disease duration: 2.9±2.6 years), and 26 healthy control (HC)(age: 57.6±10.8) subjects completed the videonystagmography (VNG) oculomotor tests including gaze, saccade, smooth pursuit and optokinetic. Motor disability of patients were assessed using the UPDRS-III (PD: 20.1±10.4; PSP: 24.2±6.2). Inclusion criteria were: Mini-Mental State Examination (MMSE)≥ 24 for all groups and Hoehn & Yahr stage II for patients.Results: Vertical saccade latency in PSP was significantly longer compared with PD or HCs (p< 0.001) and horizontal …
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