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The auditory event related oscillations are diminished and correlate with hippocampal volumetry in mild cognitive impairment   
Yazarlar (8)
Yener Görsev Gülmen
Pınar Kurt
Berrin Çavuşoğlu
Derya Durusu Emek
Gülşah Aktaş
Emel Ada
Bahar Güntekin
Erol Başar
Devamını Göster
Özet
Background: Amnestic mild cognitive impairment (MCI) is a pre-dementia stage in majority. Event-related oscillations (ERO) might be used for detection of cognitive deficits. Our group showed decreased delta target ERO in AD previously. We investigated whether the same prevails for MCI, and ERO correlate to brain volumetry. Method: MCI subjects (n= 22) and age-matched healthy controls (HC)(n= 21) were investigated by auditory ERO. The maximum target delta peak-to-peak amplitudes (0.5-2.2 Hz) were measured in+ 300-800 msec. Volumetric measurements of magnetic resonance images were performed using a semi-automatic lesion annotation and volume measurement tool (LAVA, mimlabs) in 11 MCI and 10 HC subjects.Results: The oddball target delta response was 47-62% lower in MCI over fronto-central-parietal regions. Left hippocampal and total brain volumes were lower in MCI. Left hippocampal …
Anahtar Kelimeler
Bildiri Türü Tebliğ/Bildiri
Bildiri Alt Türü Özet Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum)
Bildiri Niteliği Alanında Hakemli Uluslararası Kongre/Sempozyum
Bildiri Dili İngilizce
Kongre Adı 2012 Annual Meeting of the American Neurological Association in partnership with Association of British Neurologists
Kongre Tarihi 07-10-2012 / 09-10-2012
Basıldığı Ülke
Basıldığı Şehir
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 1

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