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Beta oscillatory responses in healthy subjects and subjects with mild cognitive impairment upon applicationof stimuli with cognitive load   
Yazarlar (5)
Bahar Güntekin
Derya Durusu Emek
Pınar Kurt
Görsev Yener
Erol Başar
Devamını Göster
Özet
The aim of the present study was to investigate the role of beta oscillatory responses upon cognitive load in healthy subjects and in subjects with mild cognitive impairment (MCI). The role of beta oscillations upon cognitive stimulation is least studied in comparison to other frequency bands. The study included 17 consecutive patients with MCI (mean age= 70.8±5.6 years) according to Petersen's criteria, and 17 age-and education-matched normal elderly controls (mean age= 68.5±5.5 years). The experiments used a visual oddball paradigm. EEG was recorded at 30 cortical locations. EEG-evoked power, inter-trial phase synchronization, and event-related beta responses filtered in 15–20 Hz were obtained in response to target and non-target stimuli for both groups of subjects. In healthy subjects, EEG-evoked beta power, inter-trial phase synchronization of beta responses and event-related filtered beta responses were significantly higher in responses to target than non-target stimuli (p< 0.05). In MCI patients, there were no differences in evoked beta power between target and non-target stimuli. Furthermore, upon presentation of visual oddball paradigm, occipital electrodes depict higher beta response in comparison to other electrode sites. The increased beta response upon presentation of target stimuli in healthy subjects implies that beta oscillations could shift the system to an attention state, and had important function in cognitive activity. This may, in future, open the way to consider beta activity as an important operator in brain cognitive processes.
Anahtar Kelimeler
Bildiri Türü Tebliğ/Bildiri
Bildiri Alt Türü Özet Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum)
Bildiri Niteliği Alanında Hakemli Uluslararası Kongre/Sempozyum
Bildiri Dili İngilizce
Kongre Adı 68th Annual Scientific Meeting of the Society-of-Biological-Psychiatry
Kongre Tarihi 16-05-2013 / 18-05-2013
Basıldığı Ülke
Basıldığı Şehir
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Google Scholar 2

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