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| Özet |
| Early diagnosis of Alzheimer’s Disease (AD) is an important topic of current research. Electrophysiological methods provide through its high time resolution property to monitor the changing brain dynamics in cognitive impairments. There are several strategies available for measuring cognitive changes, including spontaneous electroencephalography (EEG), sensory-evoked oscillations and event-related oscillations (ERO). The most common finding in spontaneous EEG of AD is decrease of fast and increase of slow frequencies over posterior regions. The motor cortex hyperexcitability has been shown by transcranial magnetic stimulation (TMS) studies. The sensory-evoked oscillations reflecting sensory network indicates a visual sensory cortex hyperexcitability in AD. Event-related oscillation studies reflecting activation of a cognitive network imply decreased responses in fronto-central regions of the brain in delta and theta frequencies of AD patients. Decrease in ERO coherence in wide connections in alpha, theta and delta frequency ranges is observed in mild AD patients. The research of all these electrophysiological multimodal methods is one of the most prompt goal of the electrophysiologists. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli ulusal dergilerde yayınlanan tam makale |
| Dergi Adı | Turkiye Klinikleri J Neurol-Special Topics |
| Dergi Tarandığı Indeksler | ISI Web |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2012 |
| Cilt No | 5 |
| Sayı | 3 |
| Sayfalar | 58 / 64 |
