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Use of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?    
Yazarlar (6)
Ayhan Kalyoncu
T.C. Maltepe Universitesi, Türkiye
H. Mirsal
T.C. Maltepe Universitesi, Türkiye
Ö Pektaş
T.C. Maltepe Universitesi, Türkiye
N. Ünsalan
T.C. Maltepe Universitesi, Türkiye
D. Tan
T.C. Maltepe Universitesi, Türkiye
Prof. Dr. Mansur BEYAZYÜREK Prof. Dr. Mansur BEYAZYÜREK
T.C. Maltepe Universitesi, Türkiye
Devamını Göster
Özet
Comorbid alcohol dependence is common in patients with schizophrenia and is associated with a variety of serious adverse consequences. Although case reports exist concerning the positive impact of lamotrigine addition on clozapine treatment in resistant schizophrenia, a review of the literature fails to document any evidence regarding a combination of the two in the treatment of patients with schizophrenia and comorbid alcohol dependence. In the present study, we present three cases in which patients with resistant schizophrenia and comorbid alcohol use disorder were given lamotrigine to augment clozapine. Our findings suggest that clozapine plus lamotrigine may be helpful in reducing alcohol consumption and craving among patients with schizophrenia and comorbid alcohol dependence. © 2005 British Association for Psychopharmacology.
Anahtar Kelimeler
Alcohol dependence | Clozapine | Craving | Lamotrigine | Schizophrenia
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Journal of Psychopharmacology
Dergi ISSN 0269-8811 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 05-2005
Cilt No 19
Sayı 3
Sayfalar 301 / 305
DOI Numarası 10.1177/0269881105051542