Use of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?
Yazarlar (6)
Ayhan Kalyoncu T.C. Maltepe Universitesi, Türkiye
H. Mirsal T.C. Maltepe Universitesi, Türkiye
Ö Pektaş T.C. Maltepe Universitesi, Türkiye
N. Ünsalan
T.C. Maltepe Universitesi, Türkiye
T.C. Maltepe Universitesi, Türkiye
D. Tan T.C. Maltepe Universitesi, Türkiye
Prof. Dr. Mansur BEYAZYÜREK T.C. Maltepe Universitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Psychopharmacology (Q4) | ||
| Dergi ISSN | 0269-8811 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2005 |
| Cilt / Sayı / Sayfa | 19 / 3 / 301–305 | DOI | 10.1177/0269881105051542 |
| Makale Linki | https://journals.sagepub.com/doi/10.1177/0269881105051542 | ||
| UAK Araştırma Alanları |
Ruh Sağlığı ve Hastalıkları
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| Özet |
| Comorbid alcohol dependence is common in patients with schizophrenia and is associated with a variety of serious adverse consequences. Although case reports exist concerning the positive impact of lamotrigine addition on clozapine treatment in resistant schizophrenia, a review of the literature fails to document any evidence regarding a combination of the two in the treatment of patients with schizophrenia and comorbid alcohol dependence. In the present study, we present three cases in which patients with resistant schizophrenia and comorbid alcohol use disorder were given lamotrigine to augment clozapine. Our findings suggest that clozapine plus lamotrigine may be helpful in reducing alcohol consumption and craving among patients with schizophrenia and comorbid alcohol dependence. © 2005 British Association for Psychopharmacology. |
| Anahtar Kelimeler |
| Alcohol dependence | Clozapine | Craving | Lamotrigine | Schizophrenia |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 41 |